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A broad environmental sampling from worldwide geographical locations coupled with experimental biochemical validation and comparative genomic analysis allowed us to test metabolic and evolutionary hypotheses difficult to approach by using sequence data from only a few environments.
They also implied that by using sequence data there should be no missing heritability.
By using sequence data available from Arabidopsis thaliana 1001 genome project, we further investigated sequence polymorphisms in the core cold stress regulon genes.
We have successfully shown that, by the use of 454 flow data, a higher rate of artificial duplicates can be identified than by using sequence data only.
A modified primer pair was designed for this region (nikB) by using sequence data from pCT and other related sequenced plasmids.
Accuracy of single-, but especially multi-breed genomic prediction, could be increased by using sequence data, since the causative mutations are probably included in the dataset.
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Fortunately, due to the low sequencing cost, small RNA and RNA sequencing are routinely processed and we may be able to infer regulation relationships between miRNAs and mRNAs more accurately by using sequencing data.
This work shows that by applying a simple approach using sequence data from multiple core housekeeping loci, we can resolve those clusters, provided such clusters exist.
Two data quality issues are immediately encountered when using sequence data produced by others and from several different researchers: genome annotation and sequence quality.
Moreover, Cameroon might be an area where the M and S forms of A. gambiae have achieved one of the highest level of genetic differentiation observable throughout the species range, as was first described by Wondji et al. [ 61] using microsatellite data and further expanded by Turner et al.[ 62, 66], using sequence data.
These findings are similar to those recently described by Snijder et al., who used sequence data from the replicase genes (5,487 bp) in ORF1b and suggested that the SARS-CoV was most closely related to and possibly an early split-off from group 2 CoV (20 ).
More suggestions(16)
by using sequence annotations
by uploading sequence data
by using sequence alignments
by using sequence probes
by combining sequence data
by using compensation data
by using user data
by examining sequence data
by using location data
by having sequence data
by using sequence fragments
by comparing sequence data
by using sequence identifiers
by using census data
by analysing sequence data
by missing sequence data
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