Supplementary analyses were also performed by using relapse-free survival as an outcome variable; relapse-free survival time was defined as the number of years between the date of diagnosis of breast cancer and the date of any type of relapse, including local, regional, and distant relapses of the disease.
But most people with drug and alcohol dependence who stop using relapse at least once before becoming stably abstinent, and many relapse multiple times.
Three proteins were successfully differentiated between patients with and without prostate cancer and patients with and without relapse by using MRM.
The approach I wish to highlight here, however, is prevention of relapse by using treatments that diminish the impact of drug-associated stimuli on drug seeking – although this is not to underestimate the impact of drug contexts, reviewed elsewhere (Crombag et al., 2008; Badiani, 2013; Bossert et al., 2013).
Both interventions teach participants to prepare to overcome barriers (e.g. time commitments, family disagreements, economics, behavior relapses) by using problem solving and goal-setting skills.
Probabilities of NRM and relapse were calculated by using cumulative incidence curves to accommodate competing risks.
Prognostic factors for imaging-detected relapse were studied by using univariate log-rank tests and multivariate Cox model analyses; proportional hazard assumptions were checked using graphical methods.
By using serial chimerism analysis, impending hematological relapse could be detected in advance to allow time to collect cells from the donor for DLI.
The number of tumour cells in the grafts of patients who did and did not experience relapse was compared by using the Wilcoxon rank-sum test.
An emerging strategy in these patients is to "artificially" increase the platinum-free interval by using a nonplatinum-containing regimen upon relapse, with the aim of reversing platinum resistance.
42 In the second analysis, we made a clinically pragmatic estimate by using data from case notes about relapses for the period after discontinuation from the study.
