Sentence examples for by using reference genomes from inspiring English sources

The PCAP assembled data were chosen above the PALAS assembled data because the PCAP assemblies maintain the inherent variation between strains, whereas the PALAS assemblies lose some variation by using reference genomes as templates for assembly (Liti et al. 2009).

Preliminary analysis indicated good coverage of the polymerase region of the ARCoV.2 reference sequence by the reads (quality index >40) by using reference assembly against CoV complete genomes.

The bias caused by the reference-guided variant discovery can now be solved by using multiple reference genomes (Gan et al. 2011).

Zhao et al. [ 11] show that poor sequence coverage can be overcome by using multiple reference genomes, but problematic for this approach are major rearrangements in the genomic sequences of more distantly related species.

The completion of a draft of the genome sequence of melon [ 28] gives us the opportunity to mine SNVs on a genomic scale by using the reference genome for the alignment of short reads obtained by resequencing the variability across the species.

In this paper we present a simple approach for deducing regulatory information in mammalian genomes with restricted sequence by using a reference genome.

We had Roche assemble contigs de novo rather than by using a reference genome, developed an algorithm to assemble contigs to pseudomolecules by synteny to the genome of MG1655, and wrote a custom Perl program to find polymorphisms in the aligned genomes.

By using a reference genome from the most closely related species, we converted most SNPs to successful assays.

RNA-seq can provide a more comprehensive and accurate transcriptome analysis of cotton fiber development by using the reference genome sequence of Gossypium raimondii Ulbr.

Although our proposed methods were able to detect more paralogous genes by using a reference genome like M. truncatula, using transcriptome data alone is insufficient due to incomplete sequencing and failure to capture all paralogous genes in the genome.

We identified 2,613 variable loci in this analysis by using as reference genome the prototype pandemic V. parahaemolyticus clonal strain RIMD221633 (available from GenBank, www.ncbi.nlm.nih.gov/genome/ term=vibrioparahaemolyticus) (10 ).