Sentence examples for by using mutants of from inspiring English sources

By using mutants of the beta(1 AR lacking G protein-coupled receptor kinase phosphorylation sites and siRNA directed against beta-arrestin, we show that Alp- and Car-stimulated EGFR transactivation requires beta(1 AR phosphorylation at consensus G protein-coupled receptor kinase sites and beta-arrestin recruitment to the ligand-occupied receptor.

This can be resolved in future experiments by using mutants of interest for single-strain infections.

Modulation (by using mutants and inhibitors) of Cdc42 interaction with Toca-1 and/or N-WASP affects membrane tubulation, vesicle formation and vesicle motility.

Drosophila females are an ideal system to test the specificity of an antibody to γ-H2AV because the ovaries are arranged according to developmental age and because we can easily control the presence or absence of DSBs by using mutants that block their occurrence or repair.

Xu et al. (2016) studied the "cell-free" cellulosomal system and characterized two types of cellulosomal systems by using mutants with scaffolding gene deletions.

In fact, the same results have been obtained by using mutant forms of K-Ras, known to induces resistance to IM [19], in 32Dp210BCR-ABL cells as well as in a CML patient sample with a weakly activating T58I K-Ras mutation, (Figure S4).

Green arrows indicate the genome positions of genes isolated by using mutant or transgenic plant analysis.

Our lab has recently developed a C. elegans model of ANCL by using null mutants of the worm DNAJC5 orthologue, dnj-14 [71].

Finally, by using functional mutants of CX3CR1 we provide evidence that this receptor regulates both adhesion and extravasation of breast cancer cells.

Further, by using two mutants of ROBO4 (c-ROBO4, lacking partial N-terminal and C1-ROBO4, and lacking the N-terminus completely), Kaur et al. [ 27] demonstrated that both intracellular and extracellular domains of ROBO4 are involved in the activation of CDC42.

We suspect that this death may represent apoptotic death observed by others using mutant α-hemolysin, though formal demonstration of this requires further investigation.