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In conclusion, this study demonstrated that it is possible to prepare engineered lactose particles with favourable properties (e.g. higher fine particle fraction and better drug content homogeneity) for DPI formulations by using lactose solutions with lower degree of saturation during crystallisation process.
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Engineered lactose particles were prepared by anti-solvent crystallisation technique using lactose solutions with different saturation degrees.
The amorphous formulation of RAPA and lactose (RapaLac) was prepared by thin film freezing (TFF) using lactose as the stabilizing agent in the weight ratio 1 1.
Nanocapsule suspensions were spray-dried using lactose or maltodextrin.
(a) Pure lactose, (b) dried nanocapsules using lactose (D-NC-L), (c) pure maltodextrin, and (d) dried nanocapsules using maltodextrin (D-NC-M) at × 3,000.
Nothing serious, not a real lactose intolerance but I feel better using lactose-free milk".
P. freudenreichii is traditionally split into two subspecies; the shermanii subspecies is identified by its ability to use lactose without nitrate reductase activity, whereas the freudenreichii subspecies cannot use lactose but displays nitrate reductase activity.
Many products use lactose, milk, or whey in their ingredients.
The optimum productivity was obtained by using 40 g/L lactose.
By using Plackett Burman protocol, lactose and temperature were found to be the most important factors for bacteriocin production.
By using various carbon sources (lactose, glucose, xylose, hemicellulosic hydrolysate) for strains growth, contrasted enzymatic activities were obtained.
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