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The effects of the 1998 legislation were assessed in a before and after design, by using interrupted time series.
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Design Controlled quasi-experimental study using interrupted time series analysis.
This was a quasi-experimental, longitudinal, controlled intervention study using interrupted time series analysis.
Trend analysis was performed to evaluate the overall pattern of changes on outcomes of interest over time using interrupted time series with segmented regression analysis.
Using interrupted time series analysis, we will study longitudinal changes in drug utilization and costs, medication adherence, and short-term health care use.
We also estimated outcomes using interrupted time series 51 models with all the covariates in the baseline model (see details of modeling and results in appendix 1).
To analyze the effect of the campaign, we planned a quasi-experimental design using interrupted time series (ITS) to control for secular trends [ 31- 33].
Adjusted analyses using interrupted time series models estimated the impact of the original and revised CDS interventions on administration of VTE prophylaxis.
These observations were tested using interrupted time-series (ITS) analysis.
The effect was analysed using interrupted time-series analysis with six non-intervention departments as controls.
A review of 58 studies using interrupted time-series demonstrated that two-thirds were unable to rule out significant threats to internal validity.
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