Sentence examples for by using highly specific from inspiring English sources

These could be accomplished by using highly specific and sensitive substrates, as well as direct assay methods.

In the present study, by using highly specific monoclonal antibodies to α-enolase, we confirm that ENO1 is significantly overexpressed in primary breast tumor specimens.

Further research is recommended to analyze the presence of fecal pathogens, such as gastrointestinal viruses, diarrheagenic E. coli, and human-specific Bacteriodales species, by using highly specific molecular techniques.

By using highly specific anti-SIMPLE antibodies, we found that endogenous SIMPLE is an early endosomal membrane protein, rather than a nuclear protein, or a lysosomal/late endosomal membrane protein, as previously suggested.

Microarrays on the other hand can be designed with a multitude of different probes either suitable for species identification by using highly specific probes, or for the detection of related or novel species by using probes lying within conserved regions [ 8].

Little SAAS localization and co-expression with established SCN neuropeptides were evaluated by immunohistochemistry using highly specific antisera and stereological analysis.

However, in a retrospective study of 47 metastatic melanoma from our centre, we have compared the V600 mutation detection by molecular techniques with the BRAF V600E mutant protein expression by immunohistochemical analysis using highly specific anti- BRAF V600E monoclonal antibodies and no other cases of misidentified p.V600E mutation was found [ 32].

Expression of iNOS, eNOS and cytochrome c were detected in the cryosections by immunohistochemical analysis using highly specific antibodies [ 30].

Immunoprecipitations and sequencing were carried out by Peconic LLC (State College, PA), using highly specific polyclonal rabbit anti-RBf1 (226.5) or anti-RBf2 (4.7) serum raised against C-terminus of RBf1 or RBf2 as described (Keller et al. 2005).

We analyzed α-enolase and MBP-1 expression in normal breast epithelium and primary invasive ductal breast carcinoma (IDC) from 177 patients by Western blot and immunohistochemical analyses, using highly specific anti-α-enolase monoclonal antibodies.

We found that inhibition of MAPK signaling using highly specific pharmacological inhibitors does not affect BRCA1 downregulation by MMS (Fig.S6).