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Currently, responses to gefitinib and erlotinib have become predictable by using gene analysis 19.
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The aim of this study was to investigate in vivo thyroidal response in mice to 211At exposure by using gene expression analysis to determine potential dose response relationships.
These observations could be due to the caspase-3 deficiency in the MCF-7 cells that were used in the present study which has been confirmed by using gene expression analysis.
The model allows an analysis of reproducible and quantifiable effects at the cellular level by using gene expression, protein analysis, and histology.
We compared their genomic variation and expression divergence and analyzed overrepresented genes and their functions by using gene set enrichment analysis (GSEA; Mootha et al. 2003) program.
By using gene set enrichment analysis (GSEA) we showed that many genes involved in fatty acid metabolism are up-regulated in a coordinated manner along with up-regulation of the nuclear factor PPARα (and to a lesser extent PPARγ).
Our study highlights those reactive pathways in response to high alkaline stress by using gene ontology and pathway analysis.
Random Set (RS) scoring methods were primary introduced by Efron and Tibshirani [ 6] to study the enrichment signal in gene sets analysis by using gene expression data.
Further analysis to uncover IGF-I targets in the cochlea was carried out by using gene microarrays to do a comparative analysis of the expression profiles of the developing cochlea in Igf1+/+ and Igf1−/− mice.
In addition to observing the RpoN regulon by using gene expression microarrays, we employed computational analysis using the PromScan software [ 27] to identify RpoN recognition sequence elements within the G. sulfurreducens genome.
We have previously demonstrated regulation of a host of implantation-related genes including LIF by PROK1 using gene array analysis (7).
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