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For MAE, MSPD and ethyl acetate extraction, the optimal conditions were optimized by using experimental designs.
By using experimental designs based on statistical principles, researchers can extract, from a minimum number of experiments, a maximum of useful information about the system under study.
Critical method attributes, the absorbance at 450 nm (A450) of the Nessler product as well as its variability, were evaluated as a function of critical method variables, by using experimental designs.
By using experimental designs, optimum separation was successfully achieved and five impurities of AR could be separated in 20 minutes with satisfactory resolution, linearity, and sensitivity.
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The amounts of solid sorbents for clean-up procedure were optimized by using experimental design.
Subsequently, pressure, temperature and CO2 volume were optimized by using experimental design approaches.
This analytical method was developed by using experimental design and quantitation was accomplished with the internal standard method.
The optimisation of the operational and chemical variables affecting the CL response was carried out by using experimental design strategies.
The effects of temperature, pH, salt concentration, PEG concentration and their interactions on the partition were analyzed by using experimental design 2k.
The main factors affecting the extraction efficiency (namely: irradiation power, irradiation time, number of cycles and extractant volume) were optimised by using experimental design methodology.
The optimization of the instrumental and chemical variables affecting the CL reaction was rigorously carried out by using experimental design methodology.
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