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Since GBP1 is a large GTPase which undergoes conformational changes in a nucleotide-dependent manner, we investigated the effect of GTP/GDP binding on GBP1 PIM1 interaction by using computational and biological studies.
Based on the signal of In100 element in casp-2, we have detected the In100-like sequences as a family of sequence elements associated with alternative splicing in the human genome by using computational and experimental approaches.
Moreover, several efforts by using computational and mathematical approaches have been made in investigating small molecules of DPP-4 inhibitors.
One way of solving this problem is to elucidate the mechanism of action of DBS in MDD by using computational and animal models.
We implemented an integrative approach by using computational and experimental analyses to provide a detail insight into phenotypic, genetic variation and expression diversity between BT×623 and Keller lines.
By using computational and experimental approaches we collected evidence that the species-specific events of retrotransposition and mutation created new Rap1 isoforms whose signaling capacity differs from that of their parental isoforms.
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In this work, the stability, thermodynamics and structure of the functional dimeric Fur A from Anabaena sp. PCC 7119 were studied by using computational methods and different biophysical techniques, namely, circular dichroism, fluorescence, Fourier-transform infrared, and nuclear magnetic resonance spectroscopies.
In summary, by using computational analysis and experimental approach, for the first time, we identified 125 putative wheat long npcRNAs.
In this study, by using computational analysis and experimental approach we identified 125 putative wheat stress responsive long npcRNAs, which are not conserved among plant species.
By using computational prediction and recombinant human proteasome catalytic subunit β1, we found in the present study that proteasome catalytic subunit β1 could serve as a direct target of celastrol.
Performance and hydrodynamic characteristics are investigated by using computational fluid dynamics and experimental methods.
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