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Although many modeling studies have been conducted using similar tools (3, 4, 10, 13 – 15 ), none of them have been subsequently tested by using actual data and evaluated in terms of the usefulness in practice.
In addition, it is well known that pharmacokinetic parameters are highly variable in critically ill patients because of a variety of factors [ 91], and thus whether any PD targets were actually attained by any interventions should ideally be confirmed by using actual pharmacokinetic measurements in each individual study, to better correlate with clinical and other end points.
And why is Libor not calculated by using actual rather than perceived rates?
The campaign is among several under way that seek to burnish brand images by using actual employees rather than actors.
Doug Ramsey, chief investment officer at the Leuthold Group, prefers to analyze P/E ratios by using actual average profits over the last five years, thus smoothing out extreme highs and lows in the cycle.
Standing back from the fray, we can see that much of the controversy concerns how to compare income in different countries.The answer to what is happening to world income distribution turns out to depend heavily on whether countries are weighted by population, and whether income in different countries is measured in PPP terms or by using actual exchange rates.
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DECA was evaluated by simulation using actual signals.
Supported by experiments using actual measured sea clutter signals, the SCCS approach is found to outperform the single-RBF approach.
The analysis was based on hour-by-hour simulations using actual building characteristics and previously identified utilization patterns.
Then, we wished to demonstrate improved quality of DOT images by DCA-L1 using actual functional brain imaging data taken from human in vivo measurements, as an example.
Such a proposition would need to be tested either in empirical work or by means of simulations using actual genotype data in which linkage disequilibrium is present.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com