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The identification of CNV regions (CNVRs) was performed by using a stringent procedure.
In addition, more overlapping genes may not have been identified because of a potential lack of power caused by using a stringent Q-value of 0.1.
Consequently, by using a stringent study design and powerful analytical tools, we estimate that we were able to detect a 1.5-fold change at the 0.01 alpha level for 90% of the probes with at least 91% power.
By using a stringent cut-off for hit selection, two of the 2000 compounds screened were flagged for re-screening, although only one of these, acivicin, was subsequently validated.
We have tested all 17 tetraspanin trees (Test No.1-383 No.1-383innAdditional by using a stringent branch-site model (see Methods), but only 15 were put into fileher statistic analysis (Table 2).
It then compares microenvironments in the query to those in the DBD, searching for the mutual best-scoring microenvironment pairs (between the query and every drug-binding site) with high similarity by using a stringent cutoff (S Tc) <−0.3).
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We may avoid such approximation by using a less stringent one.
By using a less stringent criterion (by taken the ration between Ski2∆ sample and Ire1∆ samplesample: we allowed a ratio of 5 or more).
By using a relatively stringent prior (π1 =0.001) on average 42 SNPs per run are selected to have an effect on the trait.
As a result, shortly after the availability of the cassava genome sequence in the Phytozome database, [ 21] revised such a pathway by using a more stringent comparative genomic protocol.
By using a less stringent level of 20% FDR (False Discovery Rate), we observed four pathways (Supplementary Material, Table S1), containing 141 unique genes, which is 0.7% of all the known genes in human genome.
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