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It is a simulation approach iteratively combining the variability of different diet patterns by using a simplex mixture design.
To obtain good irradiance uniformity on the solar cell, optimal prism displacements are optimized by using a simplex algorithm for collimated incident sunlight based on different prism focus on different position principles.
In this method, phase-space distributions at the extraction channel of the synchrotron were modeled with 8 parameters, and the best parameters were determined so as to minimize a difference between the calculated and measured beam profiles by using a simplex method.
This was accomplished by using a simplex optimization routine implemented in C [32], which searched for the set of P that minimized the negative log-likelihood value.
The Nelder-Mead method is a heuristic search that relies on approximating a local optimum for a problem with N variables by using a simplex (a polytope consisting of N + 1 vertices).
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New group interaction parameters were determined by using a modified Simplex method, minimizing a composition-based objective function.
The curve was fitted to experimental data by maximum likelihood method using a simplex search [ 36] followed by a gradient search [ 37].
Dressing development was assisted by design of experiments, using a simplex centroid design.
Kinetic and transport parameters are estimated by minimizing the sum-of-squares error between the model and experimental measurements using a simplex method.
Selection stringency can be improved by using mutant neomycin phosphotransferase II selection markers with reduced affinities for the neomycin drug [ 32, 33], by using a weak Herpes simplex virus thymidine kinase promoter [ 34], and by codon deoptimization of selection marker gene [ 35], which reduce the selection markers' activity, transcription initiation and translation rate respectively.
These motion parameters are figured out by maximizing the mutual information between the pixel values of the bands using a simplex-based optimization algorithm.
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