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Finally, the algorithm was explored by using a pathway of candidate genes.
We next wanted to identify the biological processes influenced by the engagement of CD49f and HSP60, connexin 45 and CD151 in HUVECs treated with either anti-US28 or anti-UL122 antibodies by using a pathway analysis software (Pathway Studio).
By using a pathway centered approach and tissue-specific gene expression signatures, we have shown highly similar gene expression programs in corresponding human and minipig tissues.
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By using a pathway-based approach, we show that ESTs encoding photosynthetic function and ribosomal proteins are the most abundant ESTs in rapidly growing B. sudeticus cells.
In this work, we have manually assigned functions to 472 orphan genes in the metabolism of A. nidulans, by using a pathway-driven approach and by employing comparative genomics tools based on sequence similarity.
By using a pathway-based approach according to KEGG databases, we show that ESTs encoding ribosomal proteins and photosynthetic functions are the most abundantly expressed ESTs in the rapidly growing B. sudeticus cells.
Endo-siRNAs are produced by cells using a pathway very similar to that of miRNAs [ 1] and have been identified in diverse organisms including C. elegans [ 34].
Anaerobic bacteria assimilate cellodextrins from plant biomass by using a phosphorolytic pathway to generate glucose intermediates for growth.
Additional functional analysis was performed by using an Ingenuity Pathway Analysis software (Ingenuity Systems, Redwood City, CA).
Thus, the performance of DIGRE might be improved by using a better curated pathway database; (ii) to quantify genomic changes, we only used the differentially expressed genes identified at 24 h after treatment using a simple fold-change cutoff.
As a result, shortly after the availability of the cassava genome sequence in the Phytozome database, [ 21] revised such a pathway by using a more stringent comparative genomic protocol.
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