Sentence examples for by upregulating the transcription from inspiring English sources

Activation of HIF1α promotes the conversion of glucose to pyruvate and lactate by upregulating the transcription of glucose transporters (GLUT1), hexokinases (HK1 and HK2), lactate dehydrogenase A (LDHA) as well as the lactate-extruding monocarboxylate transporter 4 (MCT4) [129], supporting the shift to aerobic glycolysis.

GA induces trichome initiation by upregulating the transcription level of GL1 in Arabidopsis.

FOXF2 deficiency enhances metastatic ability of BLBC cells via activating an EMT program by upregulating the transcription of TWIST1.

Here we report that XIAP and cIAP1 induce autophagy by upregulating the transcription of Beclin 1, an essential autophagy gene.

When the proteasome is inhibited, cells respond by upregulating the transcription of genes that encode proteasome subunits.

Flotillin-1 promotes breast cancer carcinogenesis inducing entry into the S phase of the cell cycle and by upregulating the transcription factor Foxo3a [ 16].

Activation of central CB1 receptors promotes food intake and thereby weight gain [ 175– 177] by increasing de novo lipogenesis by upregulating the lipogenic transcription factor SREBP-1c [ 178] and lipoprotein lipase activity [ 179].

It has recently been reported that NOTCH2, activated via delta-like ligand 1, inhibits the EBV lytic cycle in the EBV-infected B-cell non-Hodgkin's lymphoma line by upregulating the cellular transcription factor Zeb2, which represses BZLF1 expression.

Human basal breast cancer cells are highly plastic and can revert from a non-cancer stem cell (CSC) state to a cancer stem cell state by upregulating the EMT transcription factor Zeb1. Interestingly, the promoter region of Zeb1 is in a bivalent state in the non-CSC population and therefore it can readily switch to an active configuration in response to stromal TGF β [39].

FOXF2 deficiency enhances metastatic ability of BLBC cells by activating the EMT program through upregulating the transcription of TWIST1.

Notch is required for the mitotic to endocycle switch at stage 6 by upregulating the zinc finger transcription factor hindsight, which functions to downregulate the homeodomain gene cut (Sun and Deng, 2005; Sun and Deng, 2007).