Sentence examples for by upregulated expression of from inspiring English sources
Above changes were related to altered cell demise (apoptosis and necroptosis), as shown by upregulated expression of cleaved caspase 9, cleaved caspase 3 and RIP1/RIP3/MLKL cascade.
Hypoxia and HIF-alpha stabilisation in the retina were closely followed by upregulated expression of the downstream mediators VEGF and EPO.
Macrophages and sciatic nerve tissue in Tg+ sick mice exhibit a markedly pro-inflammatory gene expression profile, as evident by upregulated expression of FasL, IFN-γ, and IL-12.
VEGF-C/VEGFR3 signaling in NSCs is also characterized by upregulated expression of factors that are mandatory checkpoint regulators of the cell cycle.
These effects of SSd alone, radiation alone, and their combination, were accompanied by upregulated expression of p53 and BAX and downregulation of Bcl2 expression under oxia and hypoxia.
Th1 and Th17 cells are distinct lineages of proinflammatory effector/memory cells, imprinted for reexpression of interferon-γ (IFN-γ) and interleukin-17 (IL-17), by upregulated expression of the transcription factors T-bet and RORγt, respectively.
Our data revealed that inhibition of BRF2 could suppress the metastatic ability, while knocking down of BRF2 expression by siRNA inhibited the activity of tumor cell migratory and invasive properties in vitro and is companied by upregulated expression level of E-cadherin and downregulated expression level of N-cadherin.
Taken together, the increased stressful growth arrest conditions imposed by Pb-TCMC-trastuzumab induced cell death-associated genes, evidenced by the upregulated expression of genes, including the GADD45 family and p73 involved in regulation of the apoptotic processes.
These effects of castration were reversed by testosterone replacement, as indicated by decreased plasma norepinephrine, increased myocardial norepinephrine and density of TH-labeled nerve fibers, as well as by an upregulated expression of myocardial TH protein.
These dysfunctional NK cells are characterized by the upregulated expression of several inhibitory receptors, such as PD-1 (Keir et al., 2008; Benson et al., 2010), and the downregulation of critical, stimulatory NK receptors, such as NKG2D (Krockenberger et al., 2008).
The pattern of upregulated genes clearly reflects an ongoing inflammatory response, as shown by the upregulated expression of several endothelial adhesion molecules, chemotactic proteins and cytokines.
