Sentence examples for by underlying changes in from inspiring English sources

The difference in [18F]FDG uptake between the treatment and control group was supported by underlying changes in gene expression of GLUT1.

Best characterised for T cells, differentiation into T helper 1 (Th2), Th17 Th17 and regulatory T cells (Treg) is governed by underlying changes in DNA/histone methylation and/or histone acetylation (as recently reviewed by Janson et al. 2009).

Moreover, it could well be that the weak association between DNAm and gene expression observed in whole blood (18) is entirely driven by underlying changes in blood cell-type composition with no direct effect on cell function.

The model we developed suggests that the canonical ERK-MAPK signaling cascade operating in a cell-autonomous manner (i.e. without direct cell-cell interactions or long range diffusion of ERK signaling molecules) can reproduce general features of the immunofluorescence data measured in situ, when driven by underlying changes in the surrounding tissue microenvironment.

This allowed for a 'difference in difference' analysis to be undertaken, which measures the effect of the campaign on incidence of NSCLC, by stage, while controlling for underlying changes in the diagnoses of disease not related to the campaign by adjusting the change in diagnoses in the intervention area by the change observed in the control area.

Furthermore, the third cluster (Clus3) in tt4 roots was significantly enriched for metabolites contained in 'nitrogen metabolism' (Table 2), suggesting that our approach may reflect underlying changes in the metabolism by lacking of CHS in Arabidopsis.

Since the molecular mechanisms underlying changes in gene expression by carnitine supplementation in livestock and model animals are only poorly understood, the present study aimed to elucidate possible alterations in the miRNA profile following dietary supplementation with carnitine.

Previous studies have investigated the ionic mechanisms underlying changes in the ECG caused by mutations and diseased conditions.

These distinguished ISGs by cell-type specificity, kinetics, and sensitivity to tonic IFN and revealed underlying changes in chromatin configuration.

Major sales by Capital generally represent either a growing dissatisfaction with management or concerns about underlying changes in the industry, media executives note.

The discussion concerns mechanisms underlying changes in local arterial/arteriolar stiffness as well as whether stiffness is altered by changes in myogenic tone and/or wall structure.