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Caspase-3 can be induced by two primary pathways: by activation of cell surface receptors (FAS, TRAIL, TNF), or by activation of a stress response pathway leading to cytochrome C release from mitochondria and caspase-9 activation [ 13, 14, 15].
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The complement system is activated by three primary pathways (classic, alternative, and mannose-binding-lectin), each consisting of a series of serine proteases.
Stress exerts its effects on immune effectors through two primary pathways: the sympathetic adrenal medullary pathway, and the hypothalamic pituitary adrenal pathway which modulate adaptive immunity and lymphocyte migration.
I believe there are two primary pathways.
Two primary pathways of apoptosis have been established.
Cell death through apoptosis is known to occur through two primary pathways: an extrinsic pathway that involves death receptors, and an intrinsic pathway that is modulated by members of the Bcl-2 family [ 46], which consists of outer mitochondrial membrane components [ 47].
Nitrotyrosine adducts are formed in vivo by two primary reaction pathways.
The two primary signaling pathways activated by EGFR include the Ras/Raf/MEK/ERK and the PI3K/Akt axes [ 31].
These studies suggested that two primary apoptotic pathways, death receptor (extrinsic) and NMDA receptor (intrinsic -related programmed cell-death pathways, are both intrinsic -relatedtentiation by EtOH of HIV-1 gprogrammeded direct human neuronal death.
This research examines the relative induction of the two primary detoxification pathways upon exposure to nanosilver.
There are two primary apoptotic pathways: extrinsic and intrinsic.
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