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FLC is repressed by two main pathways, the vernalization and the autonomous pathways.
In animals, HCN is thought to be detoxified by two main pathways.
The latter is marked by agricultural fronts characterised by two main pathways, namely the colonial pathway and the local community pathway (Smith, et al., 1997).
From the literature, it is known that the apoptotic process can be regulated by two main pathways: the death-receptor pathway and the mitochondrial pathway.
See related research by Kwakman et al., http://ccforum.com/content/16/5/R214 Colonization of the catheter occurs by two main pathways: the extra-luminal route or the intra-luminal route.
In budding yeast and mammals, COs are controlled by two main pathways, one dependent on Mus81 and the second requiring the activities of Msh4 Msh5, two proteins with similarity to the MutS class of mismatch repair proteins (Edelmann et al. 1999; Holloway et al. 2008; Abdullah et al. 2004; Khazanehdari and Borts 2000; Ross-Macdonald and Roeder 1994) (Fig. 5).
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In C. elegans, apoptosis can be triggered by three main pathways: (a) the DNA damage pathway, the main mediator being the C. elegans p53 orthologue CEP-1 [32]; (b) the cytoplasmic stress pathway, mediated by LET-60/K-Ras [33], and (c) the physiological pathway, mediated by the Retinoblastoma (Rb -like pRb -likeIN-35 [34].
Lipid mediators are synthesized by three main pathways, cyclooxygenase, 5-lipoxygenase and cytochrome P450, by using fatty acids such as arachidonic acid (AA), eicosapentaenoic acid (EPA) and γ-linolenic acid (GLA) as substrates [ 7], but the biological anti-inflammatory activities of EPA and GLA are far beyond the simple regulation of eicosanoid production.
APP processing occurs by one of two main pathways: the non-amyloidogenic pathway, or the amyloidogenic pathway (Chow et al., 2010; Zhang et al., 2012).
In this study, the results obtained from TLC, HPLC, and UPLC/Q-TOF MS analysis showed that hydrolysis of G-Rc by BG-1 occurred through two main pathways, as shown in Fig. 10.
The investigation of the molecular bases of two major syndromes, familial adenomatous polyposis (FAP) and hereditary nonpolypsis CRC (HNPCC), has led to the identification of two main pathways by which these molecular events can lead to CRC [5].
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