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The effects of ETs on mammalian cells are mediated by two distinct subtypes of G protein-coupled receptors, ETA and ETB (Arai et al, 1990; Sakurai et al, 1990), which are expressed in various tissues and stimulate several intracellular signalling systems.
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The diverse physiological actions of DA are mediated by five distinct subtypes, which are commonly divided into two classes: the D1-like receptors (D1Rs, comprised of D1 and D5 receptors) and the D2-like receptors (D2, D3, and D4 receptors) [ 14].
ICAM-1 expression analysis by flow cytometry revealed two distinct subtypes of cells in the clinorotated group (μg group) compared to the 1 g control group and the incubator control group consisting of only one subtype, respectively).
Recent longitudinal analysis of a large KPD cohort revealed that the A−β+ phenotype includes two distinct subtypes distinguished by the index DKA episode having a defined precipitant ("provoked," with progressive β-cell function loss over time) or no precipitant ("unprovoked," with sustained β-cell functional reserve).
Long-term longitudinal follow-up of a large cohort of A−β+ KPD patients has revealed that this phenotype comprises two distinct subtypes distinguished by whether the index DKA episode had a defined precipitant ("provoked" A−β+) or no precipitant ("unprovoked" A−β+) (4).
This theory proposed the existence of two distinct subtypes ('pathways') within combined type ADHD: one characterised by inhibitory deficits and the other by delay aversion.
Taken together, these results indicate that our integrated approach can faithfully identify the two distinct subtypes from the same origin.
But to the researchers' amazement, they were expressing different genes and could be classified into two distinct subtypes.
HL consists of two distinct subtypes – classic HL (cHL) and lymphocyte predominant HL (LPHL).
Essex Lopresti subdivided these fractures into two distinct subtypes.
Two distinct subtypes of PBL were identified and classified as oral and extraoral PBL.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com