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Among the different syntrophin isoforms expressed in skeletal muscle tissues, the α and β1 subunits are preferentially associated with dystrophin and are encoded by two different genes [34].
Remarkably, the LS function is encoded by two different genes in Brucella, with ribH1 located within the rib operon in chromosome I, and ribH2 located in chromosome II (Table 1).
Human ASGPR is a hetero-oligomer composed of a major subunit (H1) and a minor subunit (H2) which are encoded by two different genes expressed in a molar ratio of ∼3∶1 [4]–[6].
In vivo, the five isoforms of LDH exist as combinations of two subtypes: H (predominant in heart) and M (predominant in liver and skeletal muscle), encoded by two different genes.
In Ae. aegypti, the EAT37247 and EAT37246 are encoded by two different genes, but their primary sequences are essentially the same except that residue Asn235 in EAT37246 is replaced by Tyr235 in EAT37247.
GSK-3 has two isoforms, α and β, which are coded by two different genes (Jope and Johnson, 2004).
Similar(33)
Now characterized by gene sequencing and restriction isotyping in many members of the families of the original carriers, the variant isoform has actually been found to be determined by two different gene mutations.
The operational criterion for instantiating a gene model in the Arabidopsis genome is for a gene structure to be predicted similarly by two different gene-prediction programs.
Although all 5 miR-200 family members, coded by two different gene clusters, were tightly clustered in the NCI60 cell lines, the situation was much different in the three primary cancers.
Hence, time dependent regulation of subchondral bone loss was assessed by two different gene markers specific for osteoclastic bone resorption, CatK and tartrate resistant acid phosphatase (TRAP) using real-time PCR of tissue slice #1.
Intriguingly, NAS1, which was previously thought to be one of three NAS isoforms in maize [ 21], was identified as being differentially expressed in the comparison of B73 grown at 10 versus 300 μM iron and represented by two different gene identifiers (Table 3, Additional file 1: Figure S7, S8, S9 and S10).
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