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In a trial by trial analysis of blocks processed after the initial model visit, we found moderate correlations between the duration of the initial model visit and the number of consecutive 'high-memory' cycles.
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A mixed-design condition-by-trial analysis of variance (ANOVA) revealed a main effect of trial type.
Fig. S2 shows the results of a trial-by-trial analysis of selections from deck B'.
The formation of a new motor memory of novel forces may involve multiple processes working on multiple timescales [29]; our experimental design and trial-by-trial analysis of adaptation to occasional force pulses identifies the cognitive components of the fastest temporal processes of motor adaptation.
The recordings and associated trial-by-trial analysis of VOR learning were conducted in rhesus monkeys so that they could be directly compared with the in-depth, trial-by-trial analysis of monkey smooth pursuit learning described in a recent eLife paper from the Lisberger lab and two previous papers from that lab.
One approach we used to address this question was a trial-by-trial analysis of the correlation between activity in the climbing fibers and plasticity of the Purkinje cell responses during training.
The existence of such prominent behavioral changes over the course of the trials clearly argues for the use of a continuous measure in the analysis of LH behavior and favours the integration of a trial-by-trial analysis that benefits the identification of those trials that have the most statistical power, thus improving overall sensitivity and specificity of the approach.
Design: The reliability of postural sway measures was analyzed by within-subjects (Subject times Trial) analysis of variance (ANOVA).
Although the FACE trial, co-chaired by Drs. Ian Smith and Joyce O'Shaughnessy, is an open-label trial, analysis of the data in a blinded fashion will make the data from this trial comparable with that obtained in a single-blinded trial.
The results of our trial-by-trial analysis suggest that error signals carried by climbing fibers contribute to the induction of plasticity during VOR-increase but not during VOR-decrease training.
Fig. 2B shows the results of a trial-by-trial analysis based on a big loss from deck B'.
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