Sentence examples for by traditional sequencing methods from inspiring English sources

Similarly, uspA1 and uspA2/2 H sequences were elucidated by traditional sequencing methods [ 42, 43].

Nonetheless, only 2 of the 31 putative disease-causing changes confirmed by traditional sequencing methods were de novo, in that they were not identified in either parent of the affected proband.

By comparing not only our, but also two other spruce transcriptome sequences created by traditional sequencing methods, to both Pinus taeda and Taxus mairei we could minimize biases that might exist in any single assembly.

Also, the PhyloChip has been shown to reveal greater diversity within a community when compared with rRNA Sanger sequencing clone libraries due to the placement of the entire gene product on the microarray compared with the analysis of up to thousands of individual molecules by traditional sequencing methods [ 39].

Intragenic deletions/duplications have been identified in a number of autosomal dominant, X-linked recessive and X-linked dominant disorders, many of which would have been missed by non-exon targeted arrays and traditional sequencing methods [ 21].

In 2005, two new sequencing technologies were introduced both based on sequencing by synthesis, which promised to replace or enhance traditional sequencing methods.

Perhaps more important than the sequencing throughput provided by this technology and its relative low cost compared with traditional sequencing methods is the type of data it generates.

Drop-out rate was 12%, comparable to traditional sequencing methods using multiple markers [ 45].

Although this is circumvented by the depth of sequencing (that is, multiple reads of the same region), it is accepted that physical validation using traditional sequencing methods is required.

Sequencing all candidate genes is currently not feasible with traditional sequencing methods because of the associated cost and time.

The traditional sequencing method yields longer but less reads.