Sentence examples for by toxic side effects from inspiring English sources

Current chemotherapy regimens are comprised mostly of single-target drugs which are often plagued by toxic side effects and resistance development.

Existing therapies include amphotericin B, fluconazole, and flucytosine, which are limited by toxic side effects and the emergence of drug resistance.

The clinical usefulness of exogenous activation of Fas, as well as of the other major death receptors (i.e., TNF and TRAIL receptors) by their respective ligands or agonists has been hampered by toxic side effects [16], [21], [32], [33].

Since high doses of cytokine are required, the treatment is often accompanied by toxic side effects.

Development of intensified regimen improved the outcome of several diseases [ 39- 41, 55, 56] but is limited by toxic side effects.

However, it is often characterized by toxic side-effects.

However, the success of these treatments is offset by the development of drug resistance and by toxic side-effects on healthy cells and tissues.

At the same time therapies that improve survival time are often accompanied by burdensome (toxic) side effects.

These medical conditions, at least in an attenuated form, may also be present in cancer patients due to issues such as general state of health, presence of viral infections and morbidity caused by the toxic side effects of therapy.

As mentioned above, certain drugs can affect pharmacokinetic function by producing toxic side effects in the liver or kidney to which elderly individuals may be more susceptible (Girgis and Brooks 1994; Larrey 2002; Muhlberg and Platt 1999).

However, this treatment approach also showed limited overall survival and was accompanied by pronounced toxic side effects (Baghi et al, 2006; Vermorken and Specenier, 2010; Tselis et al, 2011).