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Analysis of seven patients treated with first-line gemcitabine revealed a time to relapse of 193 days, as judged by time from initiation of chemotherapy until radiologically detected recurrence of the disease.
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The distribution of causes of death varied when stratified by time from TB treatment initiation.
Further stratifying treated patients by time from infection to treatment initiation, the FRR decreases as the time to treatment initiation increases: for early treatment initiation (within 6 months of infection) the average FRR is 84% (64 93%), whereas for later treatment initiation (more than 6 months after infection) it is 41% (27 57%).
We also conducted analyses stratified by time from injury to the initiation of TXA treatment (≤3 h or >3 h).
TTP was defined as the time from initiation of study medication until the earliest date of disease progression as assessed by the investigator.
Survival time was defined as the time from initiation of chemotherapy to all-cause death.
Overall survival was defined as the time from initiation of treatment until death from any cause.
Overall survival was defined as the time from initiation of treatment to death from any cause.
Overall survival time was defined as time from initiation of treatment to time of death or last follow-up.
Compliance was estimated by the medication possession ratio (MPR) and persistence by the time from treatment initiation to discontinuation with no medication refill gap for a period of 30 days or more during the period of interest.
Kaplan-Meier analysis was performed to analyze the cumulative probability of unfavorable outcome, i.e. failure, in new and previously treated patients by using time from TB treatment initiation to the last medical visit.
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