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The complement system is activated by three primary pathways (classic, alternative, and mannose-binding-lectin), each consisting of a series of serine proteases.
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Caspase-3 can be induced by two primary pathways: by activation of cell surface receptors (FAS, TRAIL, TNF), or by activation of a stress response pathway leading to cytochrome C release from mitochondria and caspase-9 activation [ 13, 14, 15].
Stress exerts its effects on immune effectors through two primary pathways: the sympathetic adrenal medullary pathway, and the hypothalamic pituitary adrenal pathway which modulate adaptive immunity and lymphocyte migration.
I believe there are two primary pathways.
Two primary pathways of apoptosis have been established.
Cell death through apoptosis is known to occur through two primary pathways: an extrinsic pathway that involves death receptors, and an intrinsic pathway that is modulated by members of the Bcl-2 family [ 46], which consists of outer mitochondrial membrane components [ 47].
Nitrotyrosine adducts are formed in vivo by two primary reaction pathways.
The model accounts for the two major primary pathways in the pyrolysis network of polycyclic alkylaromatics.
The two primary signaling pathways activated by EGFR include the Ras/Raf/MEK/ERK and the PI3K/Akt axes [ 31].
These studies suggested that two primary apoptotic pathways, death receptor (extrinsic) and NMDA receptor (intrinsic -related programmed cell-death pathways, are both intrinsic -relatedtentiation by EtOH of HIV-1 gprogrammeded direct human neuronal death.
This research examines the relative induction of the two primary detoxification pathways upon exposure to nanosilver.
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