Sentence examples for by three main pathways from inspiring English sources

In C. elegans, apoptosis can be triggered by three main pathways: (a) the DNA damage pathway, the main mediator being the C. elegans p53 orthologue CEP-1 [32]; (b) the cytoplasmic stress pathway, mediated by LET-60/K-Ras [33], and (c) the physiological pathway, mediated by the Retinoblastoma (Rb -like pRb -likeIN-35 [34].

Lipid mediators are synthesized by three main pathways, cyclooxygenase, 5-lipoxygenase and cytochrome P450, by using fatty acids such as arachidonic acid (AA), eicosapentaenoic acid (EPA) and γ-linolenic acid (GLA) as substrates [ 7], but the biological anti-inflammatory activities of EPA and GLA are far beyond the simple regulation of eicosanoid production.

FLC is repressed by two main pathways, the vernalization and the autonomous pathways.

In animals, HCN is thought to be detoxified by two main pathways.

From the literature, it is known that the apoptotic process can be regulated by two main pathways: the death-receptor pathway and the mitochondrial pathway.

See related research by Kwakman et al., http://ccforum.com/content/16/5/R214 Colonization of the catheter occurs by two main pathways: the extra-luminal route or the intra-luminal route.

In budding yeast and mammals, COs are controlled by two main pathways, one dependent on Mus81 and the second requiring the activities of Msh4 Msh5, two proteins with similarity to the MutS class of mismatch repair proteins (Edelmann et al. 1999; Holloway et al. 2008; Abdullah et al. 2004; Khazanehdari and Borts 2000; Ross-Macdonald and Roeder 1994) (Fig.  5).

Following IRI, the release of danger-associated molecular patterns (DAMPs), neo-antigen formation, and immune complex formation can activate the complement system by any of the three main pathways [ 14].

Since then, several studies have shown that vitamin D metabolites affect muscle cell metabolism through three main pathways: by mediating gene transcription; through rapid pathways not involving DNA synthesis; by the allelic variant of the vitamin D receptor (VDR).

Apoptosis can be induced by various extracellular and intracellular stimuli leading to the activation of three main pathways, the extrinsic (death receptor-mediated), the intrinsic (mitochondrial) and the endoplasmic reticulum stress-mediated pathway.

Complement is activated via three main pathways.