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Hors d'oeuvres and a raw bar are followed by three courses, each consisting of three to five platters of food served family style, with wine.
We carried out a multicenter phase II study to evaluate the activity, efficacy and tolerability, of a sequential regimen consisting of three courses of gemcitabine followed by three courses of docetaxel provided there was no evidence of disease progression.
The chemotherapy regimens used in the trial comprised three courses of epirubicin, vincristine and methotrexate (EVM) followed by three courses with mitomycin C, thiotepa and vindesin (MTV), for more details see Mauriac et al (1999).
Recently, the results of the SWOG (S0027) phase II trial using a sequential regimen of vinorelbine 25 mg m−2 on days 1 and 8 every 3 weeks for three cycles followed by three courses of docetaxel 35 mg m−2 on days 1, 8, 15 every 4 weeks in patients 70 years of age and older and in patients with PS two of any age were published (Hesketh et al, 2006).
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This study consists of two parts: Study 1 targets the two periods (1994 1998 and 1999 2012) covered by two Courses of Studies (CoS), or sets of legally-binding curriculum guidelines, while Study 2 targets 2013 to the present.
Surgery is followed by six courses of chemotherapy consisting of Paclitaxel and Carboplatin.
The toxicity produced by two courses of methotrexate separated by different intervals has been studied in matched groups of rats.
Those patients underwent thoracotomy with extended lymph node dissection (ND3α) via median sternotomy [ 10], followed by two courses of chemotherapy.
The Topo/NB protocol consisted of two courses of topotecan/cyclophosphamide followed by two courses of ifosfamide/carboplatin/etoposide (ICE) and a later course of cyclophosphamide/doxorubicin/vincristine.
One hundred and thirty-six women were randomly allocated, to one of three treatment regimens: DTX 100 plus FEC 75, alternated for eight courses (ALT); four courses of DTX 100 followed by four courses of FEC 75 (SEQ T); or four courses of FEC 75 followed by four courses of DTX 100 (SEQ F).
He enrolled to a chemotherapy program with sequential high-dose chemotherapy followed by two courses with thiotepa at myeloablative doses and autologous hematopoietic stem cell transplantation.
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