Sentence examples for by these pathways in from inspiring English sources
This result is consistent with prior studies that show similar gene expression programs are regulated by these pathways in microarray analyses [14], [55].
Thus, Ang II can still be produced by these pathways in spite of effective ACE-I.
In addition, our cDNA array analysis revealed that genes that are known to be regulated by these pathways show very similar expression patterns in ciNPCs and control NPCs, which are significantly different from that in MEFs, further supporting the idea that activation of a defined set of genes by these pathways in concert are critical for the successful transition of MEFs to NPCs.
Because prior studies demonstrate that cancers with stem-like molecular signatures have poor outcomes [ 1], it is likely that HMGA1 drives a refractory, advanced tumor by inducing these pathways in tumor cells.
Lifespan extension was achieved by the modulation of these pathways in yeast, worms, flies and mice.
We used publicly available and validated gene expression "read outs" of oncogenic pathway activation previously generated by experimentally controlled activation of these pathways in vitro [38].
Here we have summarized our and other experimental evidences showing the cytotoxic effect mediated by the pharmacological inhibition of all these pathways in PEL cell lines.
The predicted regulation of these pathways by miRNAs, as found in our study, reveals another mechanism for disruption of these pathways in TNBC.
The comprehensive framework established in this study will allow further dissection of the functional roles played by these crucial pathways in vivo in noninsect arthropods.
Moreover, the mechanisms controlled by these pathways mimic those involved in the specification of the embryonic germ layers during in vivo mammalian development.
Analysis of adult Rho GTPases signaling pathways is important as aberrant signaling by these pathways has been implicated in human diseases including cancer, neurological disorders, vascular and renal disease [70], [71], [72], [73].
