Sentence examples for by these different platforms from inspiring English sources
We show here that the integration of the information captured by these different platforms results in a more comprehensive detection of differentially regulated genes and an enhancement of the apparent biological relevance of the findings.
Then using this information, we partition gene expression into different (independent) units and use this to identify genes relevant to clinical outcome as modulated by these different platforms.
Our next goal was to determine whether over-representation of particular gene networks and canonical pathways could be found among the genes identified by the different platforms.
We demonstrate significant overlap in the affected gene sets identified by the different platforms, although biological processes were represented by only partially overlapping sets of genes.
Table 1A describes the origin of the RNA used to generate cDNA libraries sequenced by the different platforms, as well as the read number contribution of each.
Detection of SNVs and small InDels by these two different platforms demonstrated its complementary power; whereas Illumina GA provides a significant depth (67× in this case) useful for resolving many SNVs and small InDels, the length of 454 reads allows for the detection of these GVs in highly polymorphic regions.
The MAQC landmark multi site study focused on the ability to capture global differences by different platforms and in intra platform reproducibility and sensitivity, but did not address how to integrate data derived from different platforms [ 41, 42].
Deploying the calculation modules on a server machine allows the execution of these modules by clients on different platforms, which reduces the development costs.
Our proposed method takes a different approach in modeling biological relationships among molecular features measured by different platforms, by focusing on relationships at a 'gene-centric' level.
