Glial cells expressing nerve/glial antigen 2 (NG2 cells) are widespread cell populations identified by their specific expression of NG2 chondroitin sulphate proteoglycan (CSPG), which in the central nervous system (CNS) accounts for approximately 8% to 9% of the total cell population in adult white matter and 2% to 3% of total cells in adult grey matter [ 1].
pDCs are characterized by their specific expression of CD123, BDCA2, BDCA4 and ILT7 (Dzionek et al., 2000; Cao et al., 2006; Rissoan et al., 2002).
By means of a high-throughput microarray-based method for studying OR gene expression, tissue-specific expression in the olfactory sensory epithelium has been observed for most OR genes, and OR-like genes have been identified by their specific expression in nonolfactory tissues.
When expression of each receptor protein was suppressed by their specific siRNA, expression levels of the other two proteins showed a trend of down-regulation, with a higher correlation between c-Met and Axl.
Effector TH cells, differentiated from naïve T cells after TCR-mediated antigen recognition with the influence of costimulation and the instruction from specific cytokines, are classified by their specific cytokine expression and immune-modulatory functions.
Once activated, CD4 T cells proliferate and differentiate into two main subsets of primary effector cells, T helper type 1 (Th1) or Th2 cells, characterized by their specific cytokine expression pattern [ 6].
Following activation, CD4 T cells proliferate and differentiate into two main subsets of primary effector cells, T helper 1 (Th 1) and Th 2 cells, characterized by their specific cytokine expression patterns [ 15].
Two groups of tumours (Group A and Group B) could be clearly distinguished by their specific HSP/GRP protein expression patterns.
An important role for other PRDM genes in embryonic development has been described through functional studies in different animal models, and is further supported by their specific and restricted pattern of expression during development [16], [17], [18].
As previously stated, AZFc genes correspond to functional determinants of spermatogenesis, as evidenced by their germline-specific expression and by the fact that their deletion conveys phenotypical consequences only for the gametogenic tissue (Lahn and Page, 1999, 2002; Tse et al., 2003; Stouffs et al., 2004; Huang et al., 2008; Kim et al., 2009).
We used average linkage clustering to group Type II genes by their tissue-specific expression patterns.
