Sentence examples for by their low expression from inspiring English sources

Five of these, CDH1 (E-cadherin), CLDN7 (Claudin-7), TACSTD1 (EpCAM), IRF6 and KRT8 (Keratin-8) have been previously implicated by their low expression in claudin-low cancers and/or in EMT in vitro [25], [26], [27].

Adult murine HSCs can be prospectively enriched by their low expression of multiple lineage markers (LIN−) including CD127, and high expression of c-Kit (hereafter, Kit) and Sca-1, as well as several other markers [1].

Liver DCs exhibit a comparatively high threshold for stimulation by LPS, which may be explained by their low expression of TLR4.

In this study, we show that AIRE promotes the expression of genes that can be characterized by their low expression levels and lack of transcriptionally active epigenetic modifications.

The involvement of PXR and CAR in fibrogenic processes was further underlined by their low expression in hepatitis C patients with advanced fibrosis.

While Olfr287 was the only ORs showing convincing responses, analysis of Olfr166 and Olfr558 were limited by their low expression at the cell membrane.

The signaling machinery of both TCRalphabetaCD8alphaalpha and TCRgammadelta IEL is constructed differently than other IEL and peripheral T cells, as evidenced by their low-level expression of the linker for activation of T cells and high expression of the non-T cell activation linker, which suppresses T cell activation.

Our decision to use RACE to verify the expression and structure of these un-annotated genes was necessitated by their low level of expression and uncertain gene structures.

At least 3 clusters corresponding to genes preferentially-expressed in somatic cells, as evidenced by their low or null expression in isolated germ cell samples, could thus be distinguished.

For instance, Ståhlberg et al. 58 analyzed single astrocytes and single neurosphere cells by qPCR (50 cycles with optimized primers) and found two sub-populations distinguished by their low or high expression of marker genes, where the highest counts exceeded 40,000 for the Vimentin or GFAP transcripts.

The higher sequence divergence of SSA3/SSA4 pair could have resulted from longer evolutionary history due to their earlier origin (fig. 2 C), whereas their higher codon bias could be explained by their relatively low expression levels observed under optimal growth conditions (table 2).