Sentence examples for by their functional annotations from inspiring English sources
Many of these modules are consistent with or supported by their functional annotations or their previously known involvement in cancer.
We clustered these 84 genes by their functional annotations and identified 8 partially overlapping functional clusters.
Finally, we applied the proposed method to two breast cancer patient datasets to identify cooperative transcriptional regulatory networks associated with recurrence of breast cancer, as supported by their functional annotations.
On the other hand, several methods rely on functional similarities between candidate and disease genes [ 15], for example, some methods measured similarity between genes by their functional annotations [ 16] (e.g., Gene Ontology (GO) [ 17]).
It provides different graphs of miRNA enrichment associated with up- or down-regulated transcripts and different summary tables about selections of mRNA targets and their functional annotations by Gene Ontology.
Abundance values of all the transcripts, along with their functional annotations by NCBI BLAST results and their corresponding Krishna Tulsi genomic scaffold, show several genes involved in the synthesis of specialized metabolites implicated to be of medicinal value (Additional file 19: Table S8).
There is a need for a centralized online platform that allows manual curation of gene-models and their functional annotation by experts.
To assess the reliability of these meta-clusters, we evaluated their functional annotation by examining the overlap of GO terms for each cluster of co-expressed genes.
To explore whether the same pathways were also overrepresented in disease-specific CNVs detected in ASD samples by other studies (15, 16, 27, 28), we downloaded the genes in those CNVs and analyzed their functional annotation by the ConsensusPathDB.
The most widely used tools for functional profiling classify genes into 2 by 2 contingency tables according to their functional annotation (functional module membership) and to the list to which they belong to.
The 662 genes associated with the modification of 128Q-neuron dysfunction appeared to encompass a variety of biological processes (cell death, protein folding, intracellular transport, metabolic processes, response to stress, stress-activated pathways) that may have a role in neurodegenerative disease pathogenesis as suggested by their functional classification using GO annotations.
