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Genes were considered to be validated by the validation dataset if an FDR adjusted p-value < 0.05 was reached.
Differentially expressed genes are considered to be validated by the validation dataset if the FDR adjusted p-value is smaller than 0.05.
Differentially expressed pathways are considered to be validated by the validation dataset if the FDR adjusted p-value is smaller than 0.05.
Pathways were considered to be validated by the validation dataset if an FDR adjusted p-value < 0.05 was reached. 2 out of 24 hybridizations were of insufficient quality, leaving 22 samples in the analysis (11 metastasized and 11 non-metastasized samples) (Table 1).
Then a k-nearest neighbor classifier [ 16] was built on the training dataset, rigorously assessed by the validation dataset and finally applied to the mouse samples to classify them (Table S2, see Additional file 1).
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The ability of each score to discriminate children with SBI was quantified in the derivation dataset, and validated in the validation dataset, by calculating the area under the receiver operator characteristics (ROC) curve (AUC) of score as a predictor of SBI.
However, we do not find an effect of sample storage time on the outcome of our validation analysis as none of these genes are statistically validated by the most recent samples in the validation dataset.
The former suggestion is also supported by the accuracy metrics of the validation dataset, for which the logs were derived from plots thinned under a different regime.
The MAPE values of the forecasts generated by the various models for the validation dataset are shown in Table 2.
We calculated the 10 year estimated risk of acquiring type 2 diabetes for each patient in the validation dataset by using multiple imputations to replace missing values for smoking status and body mass index, as in the derivation dataset.
The validation dataset encompassed by the 95 % CI was 57.8 %.
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by the validation screen
by the hmdb dataset
by the microsatellite dataset
by the validation probability
by the validation report
by the validation sample
by the mtDNA dataset
by the validation interview
by the validation team
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