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Pathway 'walks' mediated by the unique pathway ontology identifier and global connectivity views provided by the pathway suites allow users to explore the range of relationships between various types of pathways while the individual diagrams offer the picture of the molecular underpinnings of a particular pathway as presently understood.
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Furthermore, this genome resource will be able to shed some light on the unique pathways possessed by the Myriapoda for chemical defense, and investigation into the antifungal and antipredation adaptations of this underresearched lineage will be greatly aided.
"HIF-1 signaling" and "mTOR signaling" pathways are the unique pathways in Luminal-B.
We examined the 227 unique pathway pairs which are only identified by FBA and found several pathway interactions which are biologically significant.
In addition, it has been reported that, in contrast to the inhibitory effect of CAT, PACAP may induce an increase of Ca2+ entry and catecholamine release in bovine chromaffin cells by a a unique pathway distinct from nAChR, VOCs and SOCs [73].
The most represented pathways by the unique sequences were metabolic pathways (5,488 members), biosynthesis of secondary metabolites (2,904 members), plant-pathogen interaction (2,389 members), and spliceosome (1,121 members).
The pathways most represented by the unique sequences were metabolic pathways (3,381 members), biosynthesis of secondary metabolites (1,935 members), spliceosome (847 members), phenylpropanoid biosynthesis (513 members), starch and sucrose metabolism (423 members) and flavonoid biosynthesis (316 members).
The pathways with most representation by the unique sequences were "metabolic pathways", "Ribosome", and "Biosynthesis of secondary metabolites".
In this work, we identified three reasons that explain the functional differences found by CONGA: metabolic (e.g., a unique pathway), genetic (e.g., a unique isozyme), and biomass differences (Table 3, see Additional file 1: Figure S4 and text for a detailed description along with illustrated examples of CONGA results).
Thus, our results indicate that Sp1 has an important role in hUCB-MSCs migration by receiving the unique AA signaling pathway.
More studies must be undertaken to identify the signaling pathway mediated by the unique fiber composition.
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