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The somewhat heterogeneous result (p = 0.42) in this group of trials was essentially due to the more inconsistent survival data obtained by the trials using 5-FU as a combination partner.
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A thorough investigation of the potential effects and interactions between the factors is made possible by rationally planning the trials using systematic procedures, i.e. design of experiments.
Cross-validation provides a relatively unbiased estimate of the generalization capacity of the algorithm by separating the trials used for training from those used for testing.
Motility was assessed simultaneously but independently by 2 different examiners throughout the trial, using a phase contrast microscope at 100 × magnification and a heating stage (35°C).
Each trial was assigned a class by classifying each time point in the trial using the LDA classifier.
(7) Overall risk of bias For each primary outcome we will assess the overall level of evidence provided by the included trials using the GRADE approach, as incorporated in Review Manager 5. We will produce a 'Summary of findings' table (Higgins 2011b).
This growing confidence is reflected by the approval for trials using SIN-LV by both the European and American regulatory authorities [16], [17].
Those trials should also be able to pick up an increased risk of pancreatic cancer that might have been missed by the smaller trials used to win approval of the drugs.
In order to clear any doubts about the general procedure, participants performed a practice run composed of six study trials followed by 12 test trials using the dummy words from the stimulus recording.
The trained bees were then presented with each of the 14 single odorants (unrewarded), interspersed by rewarded training trials using the complex mixture.
The trained bees were then presented with each of the 14 single odorants (unrewarded), one after the other in random sequence, interspersed by rewarded training trials using the complex mixture.
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CEO of Professional Science Editing for Scientists @ prosciediting.com