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However, the use of endothelial keratoplasty is limited by the technical difficulty of the procedure, a shortage of available grafts, and the potential for graft failure or rejection.
Studies on the feasibility of immunotherapeutic strategies in bone tumors are often hampered by the technical difficulty to isolate viable fresh tumor cells for functional testing.
This may be explained by the technical difficulty, inter-laboratory reproducibility and cost of using flow cytometry to analyse DNA content.
As a consequence, the prognostic value of the variable "preservation of the cervix" seems to be confounded by the technical difficulty of the procedure.
Unfortunately progress in testing these genes' functions at the experimental level has been hampered by the technical difficulty in manipulating them.
Finally, implant performance is potentially confounded by the technical difficulty of inserting the implant, the knowledge and abilities of the surgeon inserting them, and the complexity of the cases.
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Were users spooked away by the technical difficulties, or did the simulated shortages play out in their favor by further increasing demand?
The biomechanical advantage of reconstruction nailing is outweighed by the technical difficulties involved in accurately placing the proximal screws into the head and neck [11].
This may be explained by the technical difficulties and the extremely rarity of performing two major operations in a single patient at different times.
In our study, matK provided among the highest species resolution of any single region; however, its success is complicated by the technical difficulties in retrieving sequences (Table 1).
At first glance this appears surprising but could be explained by the technical difficulties of exploring a field where conditioned and conditioning stimuli overlap and vary in the same direction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com