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The uptake in A431 was low throughout the xenograft, as indicated by the surface plot in Fig. 4e.
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Four critical pairs giving partially overlapped peaks are identified and multiresponse optimisation is carried out by analysing the surface plot of a global resolution defined as the average of the resolutions of the critical pairs.
Significant interactions between the three experimental factors were confirmed by the surface plots, interaction plot and ANOVA.
The surface plot was generated by fitting the different coefficient values (Table 2) for PDE of C-SLN nanoparticles in Eq. (1) (Fig. 4).
The surface plots illustrated by the equation are presented.
The surface plots also reveal that by increasing the extraction temperature to higher levels, the amounts of phenolic gradually dropped and this might be explained by the fact that the final equilibrium between the solvent concentrations in the plant matrix and the temperature will be achieved after a certain concentration level [22].
In this model, time-lapse video sequences of single retinal areas over 5 h revealed a random distribution and appearance of apoptotic and necrotic cells, which was particularly highlighted by the 3D surface plot (Supplementary Video 2), and the average intensity projections of the time-lapse sequence shown in Figures 2f and g (generated by ImageJ RGB Zprojector plugin).
Thus, the effects of these parameters on the MPKSF As adsorption was shown by the response surface plots using two parameters simultaneously while the remaining parameters were set at their center points.
As shown by the response surface plots, it revealed that as the initial concentration increases, some of the percentage removal data showed increasing pattern while other percentages removal data became slightly decreased.
Effect of experimental parameters on the NP degradation rate constant was established by the response surface plots.
The relationship between the dependent and independent variables is further elucidated by constructing the response surface plot.
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