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This view is supported by the striking decrease in CD4+/Foxp3+ Tregs in chronically treated Mutyh−/− mice.
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Given the striking decrease in thymic cellularity in Lmna-/ mice, we predicted a decrease in the proportion of the predominant CD4+CD8+ double-positive (DP) thymocyte population.
However, the striking decrease in HAT cases from 1998 to 2003 cannot be explained by decreased case-detection efforts because the number of persons screened in the same period doubled.
We have previously reported that the reduction in testis size in SCARKO mice as compared to littermate controls is accompanied by a striking decrease in tubular diameter (down to 61% of the control on day 50) and an even more marked decrease in lumen formation (down to 32% of the control when expressed as a percentage of testis volume) [10].
In addition, we show that APP serves a unique, non-redundant physiological function for spine structure, as evidenced by a striking decrease in spine density selectively in APP-KO mice, in particular a reduction in the proportion of mushroom spines thought to represent mature synapses.
By immunohistochemistry, we recognised a striking decrease in the total number of nerve fibres that express the general neuronal marker PGP9.5 in the BM of diabetic patients with neuropathic (T2DM-N) and neuropathic/ischaemic complications (T2DM-NI) (Fig. 1a, ANOVA p < 0.001).
The liver of the treated mice exhibited a striking decrease in inflammation.
Such a striking decrease can be explained by the occurrence of the local HPAI outbreaks instead of the imported infections.
Compared with that of Study 1, a striking decrease in the dissimilarity for experiments on the same spectrometer was observed.
This fact is also observed in our cancer model, as determined by µCT analyses that reveal a striking decrease in trabecular bone content.
In HaCaT cells, silencing of endogenous YAP resulted in a striking decrease in the levels of endogenous ΔNp63 α.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com