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The non-parametric Fisher's Exact Test was applied after consulting by the statistical support service of the Institute of Biometrics of the University of Veterinary Medicine Hannover and the analysis was conducted with the statistic software SAS® (Version 9.2) under the assumption of unequal variances, two-tailed distributions and a significance level of 0.05.
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A more quantitative way of evaluating the phylogenetic performance of different genotyping methodologies is by comparing the statistical support for each clade.
Similarly, MetaPath identifies subgraphs of a KEGG-derived network by assessing the statistical support of phenotype associations for every edge [ 36].
This association was confirmed by our data although the statistical support was weak (p = 0.017).
The statistical support by the bootstrap or the internal branch method for both the "whole-gene" phylogeny and the NACHT phylogeny are roughly in agreement.
Covariance analyses were conducted as in Lartillot and Poujol (2011), reporting mean posterior correlation coefficients, and assessing the strength of the statistical support by estimating the posterior probability (PP) of a positive or a negative correlation between the two traits of interest.
The statistical support provided by Dr. Tavpritesh Sethi, and valuable discussions with Dr. Shantanu Sen Gupta, Dr. Balaram Ghosh, Dr. Mahendra Agarwal and Dr. Naveen Arora are acknowledged.
Also, the authors are appreciative of the statistical support provided by the late Mr. John Petkov.
We appreciate the statistical support provided by Karen Ruschke (Freie Universität Berlin, Berlin Germany).
Authors acknowledge the statistical support rendered by Dr. C. Ponnuraja, Scientist 'B', Department of Statistics, National Institute for Research in Tuberculosis.
Concordance factors provide genomic support for clades, as opposed to the statistical support provided by bootstrap values or posterior probabilities.
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