Sentence examples for by the sequential exposure from inspiring English sources

Our work describes the generation of hematopoietic progenitors from human ESC and iPSC induced by the sequential exposure to BMP-4 and bFGF [17], [19], and to a mixture of early-acting hematopoietic factors in the absence of any xenogenic compound and feeder cells.

Stalk cell differentiation is induced by the sequential exposure of cells to first cAMP and then to DIF-1.

The evidence that pre-incubation of HT-29 colon carcinoma cells with FU before SN-38 achieves synergism of action is partially in contrast with results reported by other authors, which suggest that the sequential exposure of cells to FU before IRI produces only additive activity (Mans et al, 1999).

Among the most successful examples to date is the generation of pancreatic islet progenitors devised by Kroon et al. [ 33] through the sequential exposure of hESCs to Activin A and Wnt3A, followed by the addition of keratinocyte growth factor or FGF7 to induce the formation of the primitive gut tube.

Finally, the sequential exposure to PMX followed by CPT-11 (PMX → CPT-11) appeared more efficient than the reverse sequence (CPT-11 → PMX) in inducing apoptosis in all the lines, but the IC50 values of the PMX → CPT-11 sequence were higher than those of the simultaneous exposure.

The sequential exposure to PMX followed by GEM (PMX → GEM) appeared more efficient in inducing apoptosis than the reverse sequence (GEM → PMX) in CFPAC-1 and MIA PaCa2 lines, while this schedule of treatment appeared substantially indifferent in Capan-1 line.

Our results suggest that Red recombination occurs by an annealing and replication-dependent mechanism that involves the sequential exposure of homologous chromosomal regions as the replication fork advances, with the lagging-strand homologous region unwound first.

Cytotoxicity assays were also performed using either a 0 48 h or a 48 96 h exposure, followed by analysis on day 7, for the generation of fixed ratios for the sequential exposure combination studies (data not shown).

Since vinorelbine, but not paclitaxel, was able to induce p21 expression in AI cells, we postulated that the sequential exposure of AD and AI cells to paclitaxel followed by vinorelbine might produce synergistic outcomes.

In the sequential exposure, identical triplicate samples were exposed in three consecutive fresh solutions, for 1 hr in each (50 ml each, as for the non-sequential exposure).

This is indicated for Cr VI) released during the sequential exposures (1 + 1 + 1 hr, in total 3 hr), for which the released concentrations were well above the detection limit also during the last hour of the sequential exposure.