Sentence examples for by the sequencing depth from inspiring English sources

For each feature, we normalized by the sequencing depth of the corresponding chromosome to remove the impact of potential aneuploidies.

HTS has the potential to reveal a quasi-exhaustive inventory of the RNAs present in a sample, the dynamic range of the detection sensitivity is only limited by the sequencing depth.

This suggests that filtering SNPs by the sequencing depth provides an efficient way of accounting for sequencing bias of individuals in the pools.

In addition, unlike microarray data, which are affected by the dynamic range of the scanner, sequence data have a linear dynamic range only limited by the sequencing depth.

In fact, the number of phylotypes detected in a sample, or the number of microorganisms discerned at any given phylogenetic level, was strongly affected by the sequencing depth.

Genomic loci involved in a SV (a.k.a".links") are required to be supported by a minimum number of paired-end reads as determined by the sequencing depth of coverage [ 28].

We also investigated whether de novo genome assembly could be improved by combining the sequencing depth offered by the Illumina platform with the longer scaffolds provided by 454-FLX.

These problems may be ameliorated by increasing the sequencing depth and by improving the taxonomic assignment of the sequences.

By this approach, we not only increased the method sensitivity by increasing the sequencing depth, we also decreased amplification errors and thus the background noise by combining 12 independent PCR reactions.

Two of the 26 mutations were detected by increasing the sequencing depth to 1866× along with 17 other mutations that were present in ctDNA but below the calling threshold.

Thus, in our study, the reduction of background noise and increase in detection sensitivity by increasing the sequencing depth of the method led to the same results.