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To allow for the fact that not all mutations could be detected by the screening methods used, we allowed in our analysis for a sensitivity of mutation testing parameter, giving the probability of detecting a mutation if one exists.
Germline mutations in BRCA1 and BRCA2 only explain the breast cancer risk in approximately one fourth of these families, however, it is expected that additional BRCA1/ 2 mutations still remain undetected by the screening methods used today [ 2, 3].
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b The halftone image generated by the screening method [11].
[C4mim][H2PO4] is pre-selected by the screening method, and its high extractive performance is experimentally verified.
Another caveat is that a specific defect might play an important role at one stage of infection but not at another, which is not revealed by the screening method, e.g., the inactivated target can play a role by a route of inoculation not employed.
and the resulting extracts tested by the screening method described above.
Vaccine effectiveness was evaluated by the screening method and it was 78.0%.
Whereas the original RosettaLigand method performed a full sampling of torsional degrees of freedom in the internal ligands and protein side-chains, we made modifications to enable the fast run time required by the screening method.
* Vaccination effectiveness as determined by the screening method (see Methods) # NNV: number needed to vaccinate to prevent one case (calculated as 1/attributable risk; based on equivalent annual incidence of IPD in 2003/2004. §Hypothetical value for NNV given non-significant test result Serotype confirmation was obtained for 388 (98%) of the 396 IPD isolates received in winter 2003/2004.
This is α,α,α,4-tetrachlorotoluene which indicates LRTP by three of the screening methods, namely the half-life criterion, the multimedia model and results from Brown and Wania [8], and fails the B criterion by not more than 10%.
However, because of the variability inherent in both the effectiveness (i.e: increase in DALYS saved) and cost estimates, it is unlikely that there are any significant differences in the cost per DALY generated by any of the screening methods, implying no one single method can be thought of as dominant.
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CEO of Professional Science Editing for Scientists @ prosciediting.com