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The curves below it show the degree to which the unscreened field is forced down by the screening factor through the Debye parameter k0.
Five percent of women (n = 31) identified with GDM by universal screening had no risk factors and would have remained undiagnosed.
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Remarkably, Keff is the product of the intrinsic reactivity by a screening factor S, which has an elementary geometrical meaning, namely, the ratio between the real and the apparent surface area.
Data on BC risk factors were obtained by the screening program in the corresponding round.
Given that Tef and Nr1D2b are the only transcription factors identified by the screen, we hypothesized whether they could play a central role in the activation of light-induced transcription.
The performance of the screening was measured by the Z factor (Z'): Z' = 1 3* σp+σn)/|µp-µn|, where σ is the standard deviation and µ is the mean for positive (p) and negative (n) controls.
The performance of a given approach for virtual screening is evaluated by the Enrichment Factor (EF) within the top x fraction (or 100x%) of the screened library compounds defined as: E F x = Number of true positives within top 100 x % Total number of true positives × x. (3).
Following a genome-wide screen for microRNAs regulated by the transcription factor encoded by the p53 tumor suppressor gene, the authors reported that after p53-activation the abundance of thirty-four miRNAs was significantly increased, whereas sixteen miRNAs were suppressed [ 11].
Gene redundancy would possibly affect the range of functions that might be detected by the mutant screening, and analysis of functions regulated by the transcription factors identified in the screen might reveal ones that are missed by virtue of redundancy.
The screening of important cultural factors by Taguchi method shows that initial pH had the least effect on the production of ethanol from glycerol by E. aerogenes S012.
The development of this workflow was motivated by three main factors: (1) the screening of compound collections is a widely used starting point in many drug discovery projects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com