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However, because MTX and folate are transported by the same transporter within cells and compete for FPGS for polyglutamation, it is suggested that higher intracellular folate levels may trump MTX retention and affect its polyglutamation [ 53, 54].
Because Gd-EOB-DTPA uptake is mediated by the same transporter responsible for bilirubin transport, cirrhotic patients with a high Model for End-stage Liver Diseand/orELD) score and/or an elevated serum TB level are less likely to achieve adequate Gd-EOB-DTPA-enhanced MR cholangiography for displaying biliary tree morphology [ 23].
Because Gd-EOB-DTPA uptake is mediated by the same transporter that is responsible for bilirubin transport, biliary obstruction or diminished hepatobiliary function can be suspected in patients with reduced or no visualisation of the biliary tree 20 30 min after Gd-EOB-DTPA administration [ 21, 26, 27].
In neither organ have the details of ion-dependent sugar transport been elucidated and it is still unclear as to whether the two sugars are independently transported by two distinct co-transporter carrier systems or by the same transporter.
In this study, we aimed to investigate whether FHPG and GCV are carried across the cell membrane by the same transporter.
Similar(54)
Str: the maximum similarity score between Dq and the drugs in the network of De that are transported by the same transporters of De (D5 and D7).
During intestinal absorption of nutrients, the efflux from enterocytes into the bloodstream is often performed by the same transporters as the influx (GLUT, SGLT), reflecting the higher specificity of the nutrient transporters, compared to other transporters.
They also demonstrated that uptake of FBPA into human glioblastoma cells was inhibited by high concentrations of BPA in the medium, suggesting that FBPA and BPA share the same transporter system.
The functions of other members of the same transporter class, namely ABC transporters, have also been under study.
These data are in line with observations made in rats showing that the same transporters were down-regulated by CsA in the liver at the protein level [ 34].
Because they are transported by the same hexose transporter system, each sugar was assumed to competitively inhibit the uptake of the other sugar [ 26].
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by the same operator
by the same operators
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by the same woman
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by the reconstituted transporter
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by the same algorithm
by the facilitative transporter
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by the same Creator
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