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In the sets considered there are many models (deposited by the same predictors) that are identical.
By "successful validation" we meant that the same predictors remained significant on a 5% level in a multiple regression model in the closed part (see, e.g., Altman).
Finally, the recent publication of MitImpact (Castellana et al. 2015) reports a database of the entire dataset of non-synonymous human mtDNA variants annotated with nucleotide variability available through the HmtDB resource and pathogenicity scores estimated by applying the same predictors implemented in MToolBox, with three additional ones.
The efficiency of the proposed model is compared with that of an ordinary regression model (OLR) using the same predictors.
In the validation data set the same predictors were significant.
The same predictors also remained significant for each diabetes type.
In particular, backward elimination dropped the same predictors in the same order.
Although diabetic subjects are influenced by the same positive predictors as non-diabetic subjects, we partly attribute the decline in diabetic amputations in Trondheim to the activity of the diabetic foot team.
Hence, none of the HIV/AIDS-related indicators was selected since they were used in MMR prediction for some countries; and they were not health system outcomes similar to MMR (which were affected by the same distal macrostructural predictors such as infant or child mortality rates).
However, even if tested by the jackknife cross-validation, a same predictor can still yield different success rates for different benchmark datasets.
Additionally, we demonstrated that a hypocoagulative status, determined by the same method, is a good predictor of survival in severe sepsis [ 25].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com