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To evaluate the intra-platform reproducibility, we calculated the rank-based Spearman's correlation coefficients among various miRNA profiles tested on different samples by the same platform.
To analyze a new data set generated by the same platform, we first apply MAT correction [i.e. formula (1)–(2)] to each sample, u.
Despite the huge variation of DOC, we observed a consistency of coverage profiles between samples captured by the same platform, a key characteristic of DOC that enables us to carry out CNV analysis for TR data.
The analyses performed here were designed to assess whether such probe-transcript mapping influenced expressions reported by the same platform, however no such correlation was observed either between biological or technical replicate samples.
As a control, the same S. cerevisiae and E. coli genomic DNA was sonicated into fragments of comparable size as to the mononucleosomal DNA and sequenced by the same platform.
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Likewise, Calvanesse et al. [ 43] compared the methylation status in human embryonic stem cells (hESCs), cancer cell lines, and normal human primary tissues by using the same platform as that in our study.
In inning two, we started to feel beat up by the same platforms and technologies that had enriched, empowered and connected our lives.
For samples in our family-based study, we performed genotyping for all these 6 HLA loci using a different platform, the LABType SSO kit (One lambda Inc., Canoga Park, CA, USA) (http://www.onelambda.com/), in order to prevent potential spurious association caused by the same platform-related genotyping error.
(By building on the same platform, Time says it was able to launch these new sites relatively quickly).
(By building on the same platform, Time says it was able to launch these new sites relatively quickly). There's a big story in the middle of the page, with most of the navigation pushed to the left-hand side.
One lesson learned from inter-genomics studies is that there are core molecular networks that can be identified by multiple laboratories using the same platform.
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Justyna Jupowicz-Kozak
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