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Background: Do proteins that have the same structure fold by the same pathway even when they are unrelated in sequence?
Steroids are probably synthesized in all vertebrates and in many invertebrates by the same pathway, which includes cholesterol.
Interestingly, when the double hairpin motif was excised from the glucose permease IIA domain and simulated in isolation in water it unfolded by the same pathway as the WW domain, indicating that it is tertiary interactions with the protein that alter the motif's unfolding not a sequence dependent effect on its intrinsic unfolding behavior.
Often, these are rare diseases that NIBR pursues with the philosophy that a success in a well-understood molecular pathway will lead to discoveries that apply to more common ailments affected by the same pathway.
This suggests a common regulator activated by the same pathway in both irradiated and bystander cells.
We suggest that P. torridus metabolizes MVA by the same pathway.
Similar(40)
A synthetic form of marijuana's active ingredient kills pain by targeting the same pathway as morphine, researchers report tomorrow in Nature.
Adult worms of S. japonicum possess insulin receptors that can specifically bind to insulin, indicating that the parasite can utilize host insulin for development and growth by sharing the same pathway as mammalian cells in regulating glucose uptake.
In our previous work, we found that bortezomib, a proteasome inhibitor, promoted cancer cell death by affecting the same pathway in many malignant diseases.
Social neuroscientist Claus Lamm and colleagues at the University of Vienna took a different approach to test whether pain and empathy are driven by the same pathways.
In particular, with a procedure to elicit errors in the SST, we examined whether error and non-error control were mediated by the same pathways.
More suggestions(17)
by the same approach
by the oxidative pathway
by the peculiar pathway
by the same security
by the same law
by the same woman
by the same title
by the same degree
by the fulvene pathway
by the same family
by the latter pathway
by the classical pathway
by the same group
by the same margin
by the biosynthetic pathway
by the same legis
by the same algorithm
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com