Sentence examples for by the same mutations from inspiring English sources

We next mutated both NLS3 and NLS4 by the same mutations described above (hereafter referred to as NLS-M).

The fact that ΔEa(O→C) is affected by the same mutations that affect the ΔG of the open state suggests that the transition state is similar to the open state, and hence one of the earliest structural changes to occur during channel deactivation is a conformational change at the C-terminus of KCNE1 that results in channel closure.

Widely different phenotypes (dilation, noncompaction, and hypertrophy) can be caused by mutations in the same genes or even by the same mutations [ 36, 46].

CC-stabilizing and -destabilizing mutations restricted to the polyQ stretch induced much weaker phenotypes than those determined by the same mutations in the polyA stretch.

However, they can all clearly be caused by mutations in the LMNA gene, even by the same mutations within the same family (Bonne et al., 2000; Brodsky et al., 2000).

While we found that 92% of the affected genes overlapped (5,995 genes total), these genes were not always affected by exactly the same mutations in both genomes.

In that case, though, the authors confirmed the necessity and sufficiency of the identified mutations for reversal of the growth defect by introducing the same mutations into the chromosome of the original rpoB mutant, thereby providing genetic validation of the inferred compensatory effect.

Is lactase persistence in these people caused by the same mutation – as would seem likely – and has it been under positive selection as well?

Further, the common isolating traits acquired in different populations as a result of parallel ecotypic differentiation may not necessarily be governed by the same mutation, gene or even pathway in different replicates49.

The reduction in amantadine sensitivity by the same mutation that lowers barium sensitivity suggests that even though the two blockers have radically different characters, one being a divalent ion and the other being a small molecule, both act to reduce channel function at a similar site in the filter.

Evaluation of the patient's family revealed that both of her sons were affected by the same mutation.