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The gene symbol should be derived from the full name of the gene discussed previously, and it is followed by the same locus designator assigned to the full gene name.
Under this assumption, the observed delay in external colouration could be caused by the same locus in both mutants.
Quite remarkably, two eQTLs were common to the CHI and the BURP genes, suggesting that the constitutive expression of these genes could be controlled by the same locus.
This analysis also highlighted functional heterogenity within a group of co-localized eQTLs, where colocalization can result not only from multiple transcripts affected by the same locus, but also from independent genetic effets localized on the same chromosome segment.
In this case, regulatory activity seems to be modulated by the same locus on chromosome XV regardless of whether it acts through the 5′ UTR, ORF, or 3′ UTR of its target mRNAs.
This work has demonstrated the relative frequency of this phenomenon in several vertebrate genomes, underlining its biological relevance as a means to increase functional complexity generated by the same locus sequence.
Similar(51)
Our simulations show that the power of detecting a vQTL in genome scans is largely unaffected by whether the same locus also affects the trait mean (Table 5), and we note that this includes our F2 simulation with a modest degree of informativeness from markers spaced 10 cM apart.
Salinity tolerance in salmonids from three genera is to some extent controlled by the same loci.
These positive correlations suggest that male and hermaphrodite traits were mostly determined by the same loci.
This result indicates that late GR is not controlled by the same loci as early GR, and that fewer loci with large individual effects appear to be involved in late GR, which is consistent with earlier findings in chicken [ 16].
This approach allowed us to identify upstream genetic loci that influence functioning of these specific miRNA and downstream gene expression and behavioural correlates which may be influenced by the same loci.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com